1-Methylpiperazine → HCID 67028870, compound

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The title compound was prepared according to Method D and the experimental for compound 243 from 2-(4-chlorophenyl)-3-((6-chloropyrimidin-4-yl)methyl)imidazo[1,2-a]pyridine and 1-methylpiperazine. (59 mg, 45%) m/e+=419 (M+H+). 1H-NMR (400 MHz, CDCl3, δ): 8.57 (s, 1H), 7.93 (d, 1H, D, J=7.0 Hz), 7.73 (d, 2H, D, J=8.4 Hz), 7.67 (d, 1H, D, J=8.8 Hz), 7.42 (d, 2H, D, J=8.8 Hz), 7.25 (t, 1H, D, J=7.7 Hz), 6.81 (t, 1H, D, 7.7 Hz), 6.05 (s, 1H), 4.39 (s, 2H), 3.48 (m, 4H), 2.37 (m, 4H), 2.28 (s, 3H).

Provenance & Evidence