4-azido-N-methylbutane-1-sulfonamide → HCID 61456555, compound

HRID 455294Notes

Reaction equation

HRID 455294 reaction equation
[N:1]([CH2:4][CH2:5][CH2:6][CH2:7][S:8]([NH:11][CH3:12])(=[O:10])=[O:9])=[N+]=[N-]>CO.[Pd]>[NH2:1][CH2:4][CH2:5][CH2:6][CH2:7][S:8]([NH:11][CH3:12])(=[O:10])=[O:9]

Participants

4

Reactant 1

HCID 716998554-azido-N-methylbutane-1-sulfonamide

Product 1

HCID 61456555HCID 61456555, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 4-azido-N-methylbutane-1-sulfonamide (Example 6; 202 mmol), in methanol (200 ml) was added Pd/C (20 mmol Pd). The mixture put under an hydrogen atmosphere and was stirred overnight at r.t. The mixture was filtered and concentrated. The crude product was used in the next step without further purification.

Workup

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated
  3. customThe crude product was used in the next step without further purification

Sources & evidence

ORD record
ord-156ee17ba7614877b82ac41c0a9b55e4
Source dataset
uspto-grants-2013_07
Patent number
US08497270B2

Reaction notes

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