Propargylamine → HCID 58294389, compound

HRID 455333Notes

Reaction equation

HRID 455333 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][C:7](=O)[CH2:6][CH2:5]2.[CH2:13]([NH2:16])[C:14]#[CH:15]>>[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8]3[CH:15]=[CH:14][CH:13]=[N:16][C:7]=3[CH2:6][CH2:5][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 239041PropargylamineHCID 27335536-Bromo-2-tetralone

Product 1

HCID 58294389HCID 58294389, compoundYield 69%

Procedure

The title compound is prepared from 6-bromo-2-tetralone and propargylamine following a procedure analogous to that described in Step 1 of Intermediates 1 and 2. Yield: 69% of theory; Mass spectrum (ESI+): m/z=260/262 (Br) [M+H]+.

Sources & evidence

ORD record
ord-e72ca8c463f842c9a4667d15c3756a45
Source dataset
uspto-grants-2013_07
Patent number
US08497281B2

Reaction notes

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