2-(4,4-Dimethylcyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → HCID 57666473, compound

HRID 456012Notes

Reaction equation

HRID 456012 reaction equation
Br[C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[C:4]([CH:9]2[CH2:14][C:13]([CH3:16])([CH3:15])[S:12](=[O:18])(=[O:17])[C:11]([CH3:20])([CH3:19])[CH2:10]2)[N:3]=1.[CH3:21][C:22]1([CH3:37])[CH2:27][CH2:26][C:25](B2OC(C)(C)C(C)(C)O2)=[CH:24][CH2:23]1>>[CH3:21][C:22]1([CH3:37])[CH2:27][CH2:26][C:25]([C:2]2[C:7]([NH2:8])=[CH:6][CH:5]=[C:4]([CH:9]3[CH2:14][C:13]([CH3:16])([CH3:15])[S:12](=[O:18])(=[O:17])[C:11]([CH3:20])([CH3:19])[CH2:10]3)[N:3]=2)=[CH:24][CH2:23]1

Participants

3

Reactant 2

HCID 231420132-(4,4-Dimethylcyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 576664372-Bromo-6-(2,2,6,6-tetramethyl-1,1-dioxo-hexahydro-1lambda6-thiopyran-4-yl)-pyridin-3-ylamine

Product 1

HCID 57666473HCID 57666473, compound

Procedure

The title compound was prepared from 2-bromo-6-(2,2,6,6-tetramethyl-1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-pyridin-3-ylamine (as prepared in the previous step) and 4,4-dimethyl-cyclohex-1-enyl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane according to the procedure of Example 15, step (f). Mass spectrum (APCI, m/z): Calcd. for C22H34N2O2S, 391.2 (M+H), found 391.3.

Sources & evidence

ORD record
ord-4aa5f83aac644ae096fb8af2e61ce6b4
Source dataset
uspto-grants-2013_07
Patent number
US08497376B2

Reaction notes

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