Ethylhydrazine → HCID 50915828, compound

Participants

Reaction Steps

The title compound was prepared from ethyl hydrazine and 1-[3-(7-fluoro-quinolin-6-ylmethyl)-imidazo[1,2-b]pyridazin-6-yl]-ethanone in analogy to the synthesis of example 1 in 32% yield. 1H-NMR (400 MHz, MeOH -d4) δ ppm 8.81 (dd, 1H), 8.27 (d, 1H), 7.92 (d, 1H), 7.88 (d, 1H), 7.78 (d, 1H), 7.69 (d, 1H), 7.54 (s, 1H), 7.47 (q, 1H), 4.59 (s, 2H), 3.38 (q, 2H), 2.13 (s, 3H), 1.22 (t, 3H). LCMS (method A): [MH]+=363, tR=5.32 min.

Provenance & Evidence