Acetohydrazide → HCID 50915989, compound

Participants

Reaction Steps

The title compound was prepared from acetic hydrazide and 1-[3-(7-fluoro-quinolin-6-ylmethyl)-imidazo[1,2-b]pyridazin-6-yl]-ethanone in analogy to the synthesis of example 1 in 75% yield as a white solid. 1H-NMR (400 MHz, DMSO-d6) δ ppm 8.86 (d, 1H), 8.83 (d, 1H), 8.07 (d, 1H), 7.95 (d, 1H), 7.79 (m, 2H), 7.70 (s, 1H), 7.47 (q, 1H), 4.58 (s, 2H), 2.28 (s, 3H). LCMS (method A): [MH]+=377, tR=4.83 min.

Provenance & Evidence