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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456141Generated: October 30, 2026

6-bromo-N2-(quinolin-6-ylmethyl)pyrazine-2,3-diamine → 6-Bromo-N2-(1-(7-fluoroquinolin-6-yl)ethyl)pyrazine-2,3-diamine

https://huagongshe.com/reaction/456141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-bromo-N2-(quinolin-6-ylmethyl)pyrazine-2,3-diamineHCID 45789418—
Reactant1-(7-Fluoroquinolin-6-yl)ethanamineHCID 66927079—
Product6-Bromo-N2-(1-(7-fluoroquinolin-6-yl)ethyl)pyrazine-2,3-diamineHCID 86666081—

Reaction Steps

The title compound was prepared as a white solid from 1-(7-fluoroquinolin-6-yl)ethanamine in analogy to the synthesis of compound 52.1. LCMS (method B): [MH]+=364, tR=2.38 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497368B2
Source datasetuspto-grants-2013_07
ORD IDord-763d0e03ef1541a68ee84878f084c937
Source noteuspto-grants-2013_07