Lithium Hydroxide → HCID 44205943, compound

Participants

Reaction Conditions

Reaction Steps

To 2-[6-methoxy-2′-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4′-trifluoromethyl-biphenyl-3-yl]-propionic acid ethyl ester (0.05 g, 0.09 mmol) in MeOH (2 mL) was added lithium hydroxide (1N; 1 mL, 1.0 mmol), and the reaction was stirred at 65° C. for 3 hours. The crude material was purified by preparative HPLC to give the title compound. M+H is 514.

Provenance & Evidence