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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456253Generated: October 30, 2026

HCID 70202042, compound → HCID 67773917, compound

https://huagongshe.com/reaction/456253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70202042HCID 70202042—
Solvent1,4-Dioxane hydrochlorideHCID 20443148—
ProductHCID 67773917HCID 67773917—

Reaction Steps

A solution of tert-butyl [(3R,4R)-1-benzyl-4-{(3-methylbutyl)[(4-nitrophenyl)sulfonyl]amino}pyrrolidin-3-yl]carbamate in 2N HCl dioxane was stirred overnight at room temperature. The solvent was evaporated to a minimal volume, diethyl ether was added, and the formed pellet was filtered off and washed with diethyl ether giving the crude title product which was used in the next step without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497383B2
Source datasetuspto-grants-2013_07
ORD IDord-f6b9aef1cbae4259bae2faf4cc0d9e2d
Source noteuspto-grants-2013_07