HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → N-[4-(3-Cyclopropylpropoxy)benzoyl]glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | 3-Cyclopropylpropan-1-ol | HCID 20426485 | — |
| Reactant | N-[4-(2-Cyclopropylethoxy)benzoyl]glycine | HCID 66812105 | — |
| Product | N-[4-(3-Cyclopropylpropoxy)benzoyl]glycine | HCID 66812145 | 51% |
Reaction Steps
The same reactions as in Example 9 (9a) and (9b) were conducted using methyl 4-hydroxybenzoate (6.09 g, 40.0 mmol) and 3-cyclopropylpropan-1-ol (which is the compound disclosed in Helv. Chim. Acta, (2003), 86, 865-893, 4.41 g, 44.0 mmol) to give 5.74 g of the title compound (white powder, yield: 51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497397B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-862128141eeb48d2b8b60ce32bb53b75 |
| Source note | uspto-grants-2013_07 |