HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylphenethyl alcohol → N-{4-[2-(4-Methylphenyl)ethoxy]benzoyl}glycine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylphenethyl alcohol | HCID 95294 | — |
| Reactant | N-(4-Hydroxybenzoyl)glycine tert-butyl ester | HCID 10682169 | — |
| Product | N-{4-[2-(4-Methylphenyl)ethoxy]benzoyl}glycine | HCID 66811767 | 90% |
Reaction Steps
The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (275 mg, 1.09 mmol) prepared in Example 1 (1a) and 2-(4-methylphenyl)ethanol (159 μL, 1.14 mmol) to give 306 mg of the title compound (colorless crystalline solid, yield: 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08497397B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e2330027bce847d9be392375f549a897 |
| Source note | uspto-grants-2013_07 |