HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Chlorobenzoyl)propionic acid → 1-(4-Chlorophenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Chlorobenzoyl)propionic acid | HCID 77604 | — |
| Reactant | 1-(3,4-Dimethoxyphenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione | HCID 24886334 | — |
| Product | 1-(4-Chlorophenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione | HCID 24886335 | — |
Reaction Steps
279 mg of the title compound were prepared as described for 1-(3,4-dimethoxy-phenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione, using 3-(4-chlorobenzoyl) propionic acid instead of 3-(3,4-dimethoxybenzoyl)propionic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186721B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-2b9ad58602cb43b8a84401c1488f3c53 |
| Source note | uspto-grants-2007_03 |