反应详情

温度

80 °C

A mixture of 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-3-sulfonic acid benzylamide (100 mg), hydrazine hydrate (excess) in ethanol (10 mL) was heated at 80° C. for 48 hours. The reaction was concentrated, mixed with water, the precipitate was filtered off, the filtrate was washed with dilute HCl, water, dried and concentrated to give the titled compound as a light yellow solid.

1. concentrationThe reaction was concentrated
2. additionmixed with water
3. filtrationthe precipitate was filtered off
4. washthe filtrate was washed with dilute HCl, water
5. customdried
6. concentrationconcentrated