HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 136358045, compound → HCID 136358049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 136358045 | HCID 136358045 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 136358049 | HCID 136358049 | — |
Reaction Steps
2,2-Dimethyl-propionic acid 5-nitro-3-(1H-pyrrol-2-yl)-indazol-1-yl ester (370 mg, 1.13 mmol) (from Example 28) was hydrogenated using 10% Pd/C in ethanol (35 mL) at room temperature for 2 hours. The reaction was filtered and the filtrate was concentrated to give 2,2-dimethyl-propionic acid 5-amino-3-(1H-pyrrol-2-yl)-indazol-1-yl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186716B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-bcc46733c0dc4177af5baf467b9e2724 |
| Source note | uspto-grants-2007_03 |