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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456656Generated: October 26, 2026

Hydrazine hydrate (1:1) → HCID 178524266, compound

https://huagongshe.com/reaction/456656

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
Reactantethyl 5-(2-chloronicotinoyl)-1H-pyrrole-2-carboxylateHCID 76853860—
SolventEthanolHCID 702—
ProductHCID 178524266HCID 17852426619.5%

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-2-carboxylic acid ethyl ester (0.5 g) and hydrazine hydrate (0.7 g) in ethanol was heated at 80° C. for 24 hours. The resulted precipitate was collected by vacuum filtration, washed with water and dried to give 80 mg of the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07186716B2
Source datasetuspto-grants-2007_03
ORD IDord-8b014a05f9034f4b9e1b1f3f1fd5a4da
Source noteuspto-grants-2007_03