HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456657Generated: October 26, 2026
Hydrazine hydrate (1:1) → HCID 178468778, compound
https://huagongshe.com/reaction/456657
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | ethyl 5-(2-chloronicotinoyl)-1H-pyrrole-2-carboxylate | HCID 76853860 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178468778 | HCID 178468778 | 33.9% |
Reaction Steps
A mixture of 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-2-carboxylic acid ethyl ester (0.5 g) (from Example 30) and hydrazine hydrate (0.7 g) in ethanol was heated at 80° C. for 24 hours. The precipitate was filtered off and the filtrate was concentrated to give 156 mg of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07186716B2 |
|---|
| Source dataset | uspto-grants-2007_03 |
|---|
| ORD ID | ord-8557a4859ded40aa82670f7a51415896 |
|---|
| Source note | uspto-grants-2007_03 |
|---|
