反应详情

温度

80 °C

A mixture of 5-(2-chloro-pyridine-3-carbonyl)-1H-pyrrole-2-carboxylic acid methylamide (320 mg, 1.2 mmol) and hydrazine hydrate (2 mL) in ethanol (20 mL). The mixture was heated to at 80° C. for 48 hours. The precipitate was collected by vacuum filtration, washed with ethanol and water, dried to give 80 mg (27%) of the titled compound.

1. filtrationThe precipitate was collected by vacuum filtration
2. washwashed with ethanol and water
3. customdried