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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456679Generated: October 26, 2026

Hydrazine hydrate (1:1) → HCID 178527317, compound

https://huagongshe.com/reaction/456679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
Reactant(1-benzenesulfonyl-1H-pyrrol-2-yl)-(2-chloro-pyridin-3-yl)-methanoneHCID 18436866—
SolventEthanolHCID 702—
ProductHCID 178527317HCID 178527317—

Reaction Conditions

Temperature90 °C

Reaction Steps

A mixture of (1-benzenesulfonyl-1H-pyrrol-2-yl)-(2-chloro-pyridin-3-yl)-methanone (150 mg) and hydrazine hydrate (0.15 mL) in ethanol (3.5 mL) was heated at 90° C. for overnight. The reaction was concentrated, diluted with ethyl acetate, washed with base and water, dried and concentrated to give 75 mg of the titled compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07186716B2
Source datasetuspto-grants-2007_03
ORD IDord-5d87d57c9bb84d86bdd354d24a7bbeee
Source noteuspto-grants-2007_03