反应详情

温度

90 °C

A mixture of (1-benzenesulfonyl-1H-pyrrol-2-yl)-(2-chloro-pyridin-3-yl)-methanone (150 mg) and hydrazine hydrate (0.15 mL) in ethanol (3.5 mL) was heated at 90° C. for overnight. The reaction was concentrated, diluted with ethyl acetate, washed with base and water, dried and concentrated to give 75 mg of the titled compound as a white solid.

1. concentrationThe reaction was concentrated
2. additiondiluted with ethyl acetate
3. washwashed with base and water
4. customdried
5. concentrationconcentrated