HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 4-Methyloxan-4-amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 2-Chloro-N-(4-methyltetrahydro-2H-pyran-4-yl) acetamide | HCID 18437326 | — |
| Solvent | Acetic acid ethanol | HCID 18476134 | — |
| Product | 4-Methyloxan-4-amine hydrochloride | HCID 18437372 | — |
Reaction Steps
To a solution of 2-chloro-N-(4-methyltetrahydro-2H-pyran-4-yl)acetamide obtained in Example 7-2 (630 mg) in ethanol/acetic acid (5/1, 6 mL), was added thiourea (275 mg) at room temperature. The reaction mixture was heated at reflux for 2 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186731B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-76f644a0cd824971ac16c92461794708 |
| Source note | uspto-grants-2007_03 |