HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 2,4,6-Trimethyloxan-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 2-Chloro-N-(tetrahydro-2,4,6-trimethyl-2H-pyran-4-yl)acetamide | HCID 18437325 | — |
| Solvent | Acetic acid ethanol | HCID 18476134 | — |
| Product | 2,4,6-Trimethyloxan-4-amine | HCID 18437324 | — |
Reaction Steps
To a solution of 2-chloro-N-(2,4,6-trimethyltetrahydro-2H-pyran-4-yl) acetamide obtained in Example 9-3 (1.85 g) in ethanol/acetic acid (5/1, 15 mL), was added thiourea (705 mg) at room temperature. The reaction mixture was heated at reflux for 2 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07186731B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-0406e3b2854449c3adf315cb5c868ee7 |
| Source note | uspto-grants-2007_03 |