反应详情

温度

5 °C

A mixture of 4-(2-oxazolyl)-benzaldehyde (1 eq., 6.3 gm) and N-phenyl-hydroxyamine (1 eq., 3.9 gm) was refluxed in ethanol (100 ml) for 30 minutes and concentrated to a volume of 50 ml. An equal amount (50 ml) of water was added and the mixture was cooled in a refrigerator at 5° C. overnight. White crystals were obtained, which were isolated by filtration and dried, producing 6.7 gm of 4-(2-oxazolyl)-phenyl-N-phenylnitrone.

1. concentrationconcentrated to a volume of 50 ml
2. additionAn equal amount (50 ml) of water was added
3. customWhite crystals were obtained
4. customwhich were isolated by filtration
5. customdried