HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 457634Generated: October 25, 2026
Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate → 6-Trifluoromethyloxindole
https://huagongshe.com/reaction/457634
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl 2-(2-nitro-4-(trifluoromethyl)phenyl)acetate | HCID 83569 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 6-Trifluoromethyloxindole | HCID 608487 | — |
Reaction Steps
Methyl 2-nitro-4-trifluoromethylphenylacetate (26 mg) was hydrogenated over 10% palladium on carbon and then heated at 100° C. for 3 hours. The catalyst was removed by filtration and the solvent evaporated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07189721B2 |
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| Source dataset | uspto-grants-2007_03 |
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| ORD ID | ord-8297bf6395c54394842ec4283eb5610d |
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| Source note | uspto-grants-2007_03 |
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