2-Bromopyridine → HCID 18440684, compound

HRID 457755Notes

Reaction equation

HRID 457755 reaction equation
[Cl:1][C:2]1[S:6][C:5]([C:7]([NH:9][C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[C:12](=[O:28])[N:13]([CH2:20][CH2:21][CH:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[C:14]3=[O:19])=[O:8])=[CH:4][CH:3]=1.Br[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][N:31]=1>>[Cl:1][C:2]1[S:6][C:5]([C:7]([NH:9][C:10]2[CH:18]=[CH:17][CH:16]=[C:15]3[C:11]=2[C:12](=[O:28])[N:13]([CH2:20][CH2:21][CH:22]2[CH2:27][CH2:26][N:25]([C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][N:31]=4)[CH2:24][CH2:23]2)[C:14]3=[O:19])=[O:8])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 79732-BromopyridineHCID 18440685HCID 18440685, compound

Product 1

HCID 18440684HCID 18440684, compound

Procedure

can be prepared from 5-chloro-N-{1,3-dioxo-2-[2-(4-piperidinyl)ethyl]-2,3-dihydro-1H-isoindol-4-yl}-2-thiophenecarboxamide and 2-bromopyridine

Sources & evidence

ORD record
ord-4c1c178c84aa4a8c91c392fdab8f3834
Source dataset
uspto-grants-2007_03
Patent number
US07189738B2

Reaction notes

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