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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 457808Generated: October 30, 2026

3-(4-Piperidinyl)-1H-indole → HCID 69411468, compound

https://huagongshe.com/reaction/457808

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Piperidinyl)-1H-indoleHCID 702235—
ReactantHCID 59765446HCID 59765446—
ProductHCID 69411468HCID 6941146879%

Reaction Steps

This compound was prepared following the procedure described in example 1 (part D) starting with 0.2 g (1 mmol) of 3-piperidin-4-yl-1H-indole and 0.33 g (1.3 mmol 5-bromomethyl-2-fluoro-benzoic acid ethyl ester. After ionic exchange purfication, 0.30 g (79% of yield) of 2-fluoro-5-[4-(1H-indol-3-yl)-piperidin-1-ylmethyl]-benzoic acid ethyl ester were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189741B2
Source datasetuspto-grants-2007_03
ORD IDord-9da858dcae3a4ba7a43825042ae3fd49
Source noteuspto-grants-2007_03