Ethyl 4-(1H-indol-3-yl)piperidine-1-carboxylate → HCID 69412237, compound

Participants

Reaction Conditions

Reaction Steps

This compound was prepared following the procedure described in example 13 (part B) starting with 0.47 g (1.2 mmol) of 4-(1H-indol-3-yl)-piperidine-1-carboxylic acid ethyl ester and 0.62 g (2.9 mmol) of 2-[1,4]dioxan-2-yl-ethyl methansulfonate. The reaction mixture was stirred at 40° C. for 24 hours. After standard work-up and purification, 0.47 g (51% of yield) of 4-[1-(2-[1,4]dioxan-2-yl-ethyl)-1H-indol-3-yl]-piperidine-1-carboxylic acid ethyl ester were obtained.

Provenance & Evidence