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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 457834Generated: November 3, 2026

HCID 11278467, compound → HCID 10162727, compound

https://huagongshe.com/reaction/457834

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11278467HCID 11278467—
Reactant5-Bromomethyl-2-methoxybenzoic acid ethyl esterHCID 68893946—
ProductHCID 10162727HCID 10162727—

Reaction Steps

This compound was prepared following the procedure described in example 13 (part D) starting with 2.9 g (9.2 mmol) of 6-fluoro-3-piperidin-4-yl-1-thiophen-2-ylmethyl-1H-indole and 2.7 g (11.5 mmol) of 5-bromomethyl-2-methoxy-benzoic acid ethyl ester. After standard work-up, 1.2 g (27% of yield) of the expected acid were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189741B2
Source datasetuspto-grants-2007_03
ORD IDord-b0efeb3fa6994ac099df2f41d8c07f6b
Source noteuspto-grants-2007_03