HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoromethanesulfonyl chloride → 1,1,1-trifluoro-N-(2-(4-(6-methoxy-napthalen-2-yl)-5-pyridin-4-yl-1H-imidazol-2-yl)-2-methyl-propyl)-methanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoromethanesulfonyl chloride | HCID 79000 | — |
| Reactant | HCID 18440775 | HCID 18440775 | — |
| Product | 1,1,1-trifluoro-N-(2-(4-(6-methoxy-napthalen-2-yl)-5-pyridin-4-yl-1H-imidazol-2-yl)-2-methyl-propyl)-methanesulfonamide | HCID 18440758 | 33% |
Reaction Steps
The title compound (9 mg, 33%) was prepared starting from the product of Example 2 and 1,1,1-trifluoromethanesulfonyl chloride using the method described in Example 4; MS(ES) m/e 505 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189745B1 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-ae2689ec02914ff0a820fffe4f922de1 |
| Source note | uspto-grants-2007_03 |