4-Phenylbenzoyl chloride → Methyl (2S,4EZ)-1-([1,1'-biphenyl]-4-ylcarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylate

Participants

Reaction Steps

Following the general methods as outlined in Example 4, starting from 1-tert-butyl 2-methyl(2S,4EZ)-4-(methoxyimino)-1,2-pyrrolidinedicarboxylate and [1,1′-biphenyl]-4-carbonyl chloride, the title compound was isolated, after flash-chromatography, as a mixture of two isomers as an oil in 31% yield (99% purity by HPLC).

Provenance & Evidence