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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 457936Generated: October 25, 2026

Methanol → HCID 131726296, compound

https://huagongshe.com/reaction/457936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant3-Methyl-[1,1'-biphenyl]-4-carboxylic acidHCID 14090570—
Reactant(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acidHCID 58714586—
ProductHCID 131726296HCID 131726296—

Reaction Steps

Following the general method as outlined in Example 11, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 3-methyl[1,1′-biphenyl]-4-carboxylic acid, and methanol, the title compound isolated as a mixture of two isomers in 82.3% purity by HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189754B2
Source datasetuspto-grants-2007_03
ORD IDord-523fcb85d5fb42ce860f59c2b20263d6
Source noteuspto-grants-2007_03