反应详情

Ethyl 8-(methylsulfanyl)-1-trityl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate (1.0 g, 1.99 mmol) in DCM (20 ml) was treated with trifluoroacetic acid (5 ml). The resulting mixture was stirred at r.t. for 1 hour and the solvent removed in vacuo. The residue was triturated with diethyl ether filtered and dried to provide the title compound 500 mg (96%). LC/MS (254 nm) HPLC method 2 Rt 3.62 min.

1. customthe solvent removed in vacuo
2. customThe residue was triturated with diethyl ether
3. filtrationfiltered
4. customdried