Propylamine → HCID 10607990, compound

HRID 458146Notes

Reaction equation

C(N1CCC(=O)CC1)C1C=CC=CC=1.C(N)CC.FC1C=C[C:23]([N:26]2[C:30]3([CH2:35][CH2:34][NH:33][CH2:32][CH2:31]3)[C:29](=[O:36])[NH:28][CH2:27]2)=[CH:22][CH:21]=1>>[CH2:23]([N:26]1[C:30]2([CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[C:29](=[O:36])[NH:28][CH2:27]1)[CH2:22][CH3:21]

Participants

Reactant 3

HCID 7852Propylamine

HCID 192201-Benzyl-4-piperidone

HCID 939151-(4-Fluorophenyl)-1,3,8-triazaspiro(4.5)decan-4-one

Product 1

HCID 10607990HCID 10607990, compound

Procedure

This compound was prepared from 1-benzyl-4-piperidone and propylamine in analogy of the procedure described for the synthesis of 1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one. 1-Propyl-1,3,8-triaza-spiro[4.5]decan-4-one was obtained as colorless powder: MS (ISP): 198.1 MH+.

Sources & evidence

ORD record: ord-c229654d870046ec9bcb84fa12110d55
Source dataset: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07189850B2

Reaction notes

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