HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-(2-Hydroxy-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one → Rac-8-(2-oxo-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-(2-Hydroxy-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 15925796 | — |
| Reactant | Rac-1-(3-methyl-butyl)-8-(2-oxo-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 18441754 | — |
| Product | Rac-8-(2-oxo-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 18441774 | — |
Reaction Steps
The title compound was prepared from (rac,trans) 8-(2-hydroxy-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one in analogy of the procedure described for the synthesis of rac-1-(3-methyl-butyl)-8-(2-oxo-cyclohexyl)-1,3,8-triaza-spiro[4.5]decan-4-one (Example 73d). rac-8-(2-Oxo-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one was obtained as yellow solid, MS (ISP): 328.4 MH+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189850B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-a6a0205061b7435ea0fc0ed0af99ee97 |
| Source note | uspto-grants-2007_03 |