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HRID458503

反应详情

EQUATION

反应方程式

HRID 458503 的结构方程式

REACTANTS

反应物

2
结构：CC(N)C(O)c1ccc(O)cc1.Cl
HCID518687

4-(2-Amino-1-hydroxypropyl)phenol--hydrogen chloride (1/1)

C9H14ClNO2

结构：CC(C)(C)OC(=O)COc1ccc(CC=O)cc1
HCID23119601

未命名化合物

PRODUCTS

生成物

1
结构：CC(NCCc1ccc(OCC(=O)OC(C)(C)C)cc1)C(O)c1ccc(O)cc1
HCID23119604

未命名化合物

收率 51%

PROCEDURE

实验过程

The ester 20 was prepared by condensation of tert-butyl 4-[formylmethyl]phenoxyacetate (10.0 g, 0.04 mole) with α-(1-aminoethyl)-4-hydroxybenzyl alcohol 13 (8.2 g, 0.04 mole) using the same method as described for the preparation of 5, 8, and 16. The ester 20 (8.18 g, 51%) was obtained as a yellow oil.

WORKUP

后处理

  1. customas described for the preparation of 5, 8, and 16