HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,4,4-Trimethylpentan-2-yl)piperidin-4-one → 4-Phenyl-8-(1-ethylpentyl)-1,4,8-triazaspiro[4.5]decan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,4,4-Trimethylpentan-2-yl)piperidin-4-one | HCID 12992992 | — |
| Reactant | 2-(Phenylamino)acetamide | HCID 15370319 | — |
| Reactant | 1-(1-Ethylpentyl)piperidin-4-one | HCID 22937465 | — |
| Product | 4-Phenyl-8-(1-ethylpentyl)-1,4,8-triazaspiro[4.5]decan-2-one | HCID 10131531 | — |
Reaction Steps
Example 1 was repeated except that 1-(1,1,3,3-tetramethylbutyl)piperidin-4-one which was used in Example 1 was replaced with 1-(1-ethylpentyl)piperidin-4-one as obtained in Production Example 5, and 4-{[tert-butyl(diphenyl)silyl]oxy}-(2S*)-2-[(3-fluorophenyl)amino]butanam was replaced with 2-anilinoacetamide as obtained in Production Example 4, to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192964B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-00cc0da02c384e6c8d4ca42a454b6f6f |
| Source note | uspto-grants-2007_03 |