Bromoacetyl bromide → HCID 10280135, compound

HRID 458811Notes

Reaction equation

Br[CH2:2][C:3](Br)=[O:4].[NH2:6][CH:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8]1.[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:37]=[CH:38][C:39]=1[O:40][CH3:41])[CH2:21][CH:22]1[C:28]2[CH:29]=[C:30]([O:35][CH3:36])[C:31]([O:33][CH3:34])=[CH:32][C:27]=2[O:26][CH2:25][CH2:24][NH:23]1>>[CH3:16][O:17][C:18]1[CH:19]=[C:20]([CH:37]=[CH:38][C:39]=1[O:40][CH3:41])[CH2:21][CH:22]1[C:28]2[CH:29]=[C:30]([O:35][CH3:36])[C:31]([O:33][CH3:34])=[CH:32][C:27]=2[O:26][CH2:25][CH2:24][N:23]1[CH2:2][C:3]([NH:6][CH:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8]1)=[O:4]

Participants

Reactant 3

HCID 61147Bromoacetyl bromide

HCID 123445(+-)-1-Aminoindan

HCID 184425855-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro benzo[f][1,4]oxazepine

Product 1

HCID 10280135HCID 10280135, compound

Procedure

prepared by reaction of 2-bromoacetyl bromide with rac-1-aminoindane and 5-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepine.

Sources & evidence

ORD record: ord-3b990b3aa88b46a8b8bb7a986db5e29f
Source dataset: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07192950B2

Reaction notes

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