Bromoacetyl bromide → HCID 10187866, compound

HRID 458818Notes

Reaction equation

HRID 458818 reaction equation
Br[CH2:2][C:3](Br)=[O:4].[CH3:6][O:7][C:8]1[CH:16]=[CH:15][CH:14]=[C:13]2[C:9]=1[CH2:10][CH2:11][CH:12]2[NH2:17].[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:39]=[CH:40][C:41]=1[O:42][CH3:43])[CH2:23][CH:24]1[C:30]2[CH:31]=[C:32]([O:37][CH3:38])[C:33]([O:35][CH3:36])=[CH:34][C:29]=2[CH2:28][CH2:27][CH2:26][NH:25]1>>[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:39]=[CH:40][C:41]=1[O:42][CH3:43])[CH2:23][CH:24]1[C:30]2[CH:31]=[C:32]([O:37][CH3:38])[C:33]([O:35][CH3:36])=[CH:34][C:29]=2[CH2:28][CH2:27][CH2:26][N:25]1[CH2:2][C:3]([NH:17][CH:12]1[C:13]2[C:9](=[C:8]([O:7][CH3:6])[CH:16]=[CH:15][CH:14]=2)[CH2:10][CH2:11]1)=[O:4]

Participants

4

Reactant 3

HCID 61147Bromoacetyl bromideHCID 30167414-Methoxy-2,3-dihydro-1H-inden-1-amineHCID 122679961-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine

Product 1

HCID 10187866HCID 10187866, compound

Procedure

prepared by reaction of 2-bromoacetyl bromide with rac-4-methoxy-indan-1-ylamine and 1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine.

Sources & evidence

ORD record
ord-0c7bbc55ffca4cf7b8a748966a890cf2
Source dataset
uspto-grants-2007_03
Patent number
US07192950B2

Reaction notes

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