Bromoacetyl bromide → HCID 10232540, compound

HRID 458819Notes

Reaction equation

HRID 458819 reaction equation
Br[CH2:2][C:3](Br)=[O:4].[C:6]1([CH:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]([NH2:21])[CH2:13]2)[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:43]=[CH:44][C:45]=1[O:46][CH3:47])[CH2:27][CH:28]1[C:34]2[CH:35]=[C:36]([O:41][CH3:42])[C:37]([O:39][CH3:40])=[CH:38][C:33]=2[CH2:32][CH2:31][CH2:30][NH:29]1>>[CH3:22][O:23][C:24]1[CH:25]=[C:26]([CH:43]=[CH:44][C:45]=1[O:46][CH3:47])[CH2:27][CH:28]1[C:34]2[CH:35]=[C:36]([O:41][CH3:42])[C:37]([O:39][CH3:40])=[CH:38][C:33]=2[CH2:32][CH2:31][CH2:30][N:29]1[CH2:2][C:3]([NH:21][CH:14]1[C:15]2[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:12]([C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:13]1)=[O:4]

Participants

4

Reactant 3

HCID 61147Bromoacetyl bromideHCID 122679961-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepineHCID 22346445HCID 22346445, compound

Product 1

HCID 10232540HCID 10232540, compound

Procedure

prepared by reaction of 2-bromoacetyl bromide with rac-3-phenyl-indan-1-ylamine and 1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine.

Sources & evidence

ORD record
ord-516f983cd84544119e22a517eb2d9b4e
Source dataset
uspto-grants-2007_03
Patent number
US07192950B2

Reaction notes

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