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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458839Generated: October 29, 2026

[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acid → 2-[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-N-isoxazol-5-ylmethyl-2-phenyl-acetamide

https://huagongshe.com/reaction/458839

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acidHCID 18442565—
Reactant1-(1,2-Oxazol-5-yl)methanamine--hydrogen chloride (1/1)HCID 18442593—
Product2-[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-N-isoxazol-5-ylmethyl-2-phenyl-acetamideHCID 10166856—

Reaction Steps

prepared by reaction of [1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acid with C-isoxazol-5-yl-methylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192950B2
Source datasetuspto-grants-2007_03
ORD IDord-6f83cc9a4fc14ed0b24c3b02de8155b4
Source noteuspto-grants-2007_03