Bromoacetyl bromide → HCID 10230221, compound

HRID 458869Notes

Reaction equation

HRID 458869 reaction equation
Br[CH2:2][C:3](Br)=[O:4].Cl.[NH2:7][CH:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:38]=[CH:39][C:40]=1[O:41][CH3:42])[CH2:22][C@H:23]1[C:29]2[CH:30]=[C:31]([O:36][CH3:37])[C:32]([O:34][CH3:35])=[CH:33][C:28]=2[CH2:27][CH2:26][CH2:25][NH:24]1>>[CH3:17][O:18][C:19]1[CH:20]=[C:21]([CH:38]=[CH:39][C:40]=1[O:41][CH3:42])[CH2:22][C@H:23]1[C:29]2[CH:30]=[C:31]([O:36][CH3:37])[C:32]([O:34][CH3:35])=[CH:33][C:28]=2[CH2:27][CH2:26][CH2:25][N:24]1[CH2:2][C:3]([NH:7][CH:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1)=[O:4]

Participants

4

Reactant 3

HCID 61147Bromoacetyl bromideHCID 1227642-Aminoindan hydrochlorideHCID 18442571HCID 18442571, compound

Product 1

HCID 10230221HCID 10230221, compound

Procedure

prepared according to general procedure A, by reaction of 2-bromoacetyl bromide with 2-aminoindane hydrochloride and 1-(S)-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-benzo[c]azepine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-60317eab982c466ba68ac222dc49a19d
Source dataset
uspto-grants-2007_03
Patent number
US07192950B2

Reaction notes

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