HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → N-[4-(1,3,10-trioxo-1,4,5,6,10,10a-hexahydro-acenaphtho[1,8a-c]pyrrol-2-yl)-butyl]-3-pyridin-3-yl-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | ethyl N-ethoxycarbonyliminocarbamate | HCID 220568 | — |
| Reactant | 5,6-Dihydro-1H,4H-acenaphtho(1,8a-c)pyrrole-1,3,10(2H,10aH)-trione | HCID 598548 | — |
| Reactant | N-(4-hydroxybutyl)-3-pyridin-3-yl-acrylamide | HCID 53817888 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-[4-(1,3,10-trioxo-1,4,5,6,10,10a-hexahydro-acenaphtho[1,8a-c]pyrrol-2-yl)-butyl]-3-pyridin-3-yl-acrylamide | HCID 68504233 | — |
Reaction Steps
Batch size: 4.4 g (20.0 mmol) N-(4-hydroxy-butyl)-3-pyridin-3-yl-acrylamide, 5.2 g (19.8 mmol) triphenylphosphine, 4.8 g (19.9 mmol) 7,8-dihydroacenaphthen-2(6H)-on-1,8a-dicarboximide and 3.5 g (20.0 mmol) azodicarboxylic acid diethyl ester in 65 ml THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192967B1 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-2d12e378d23a4ac486b87f5415a84974 |
| Source note | uspto-grants-2007_03 |