Oxalyl chloride → HCID 53959507, compound

HRID 458874Notes

Reaction equation

HRID 458874 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[O:18]=[C:19]1[C:23]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[C:22]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[C:21](=[O:36])[N:20]1[CH2:37][CH2:38][CH2:39][NH2:40].Cl>>[O:18]=[C:19]1[C:23]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[C:22]([C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[C:21](=[O:36])[N:20]1[CH2:37][CH2:38][CH2:39][NH:40][C:9](=[O:11])[CH:8]=[CH:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 1019843-(3-Pyridinyl)-2-propenoic acidHCID 17921838HCID 17921838, compound

Product 1

HCID 53959507HCID 53959507, compound

Procedure

Batch size: 3.4 g (23.1 mmol) 3-(3-pyridyl)-acrylic acid, 5.3 g (42,0 mmol) oxalyl chloride, 4.2 g (42.0 mmol) TEA and 7.2 g (21.0 mmol) 3-(2,5-dioxo-3,4-diphenyl-2,5-dihydropyrrol-1-yl)-propylamine•hydrochloride.

Sources & evidence

ORD record
ord-7204d912e31b4d74988caccc7db4f976
Source dataset
uspto-grants-2007_03
Patent number
US07192967B1

Reaction notes

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