Oxalyl chloride → HCID 17921856, compound

HRID 458876Notes

Reaction equation

HRID 458876 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH2:8][C:9]([OH:11])=O)[CH:2]=1.C(Cl)(=O)C(Cl)=O.[O:18]=[C:19]1[C:23]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[C:22]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[C:21](=[O:36])[N:20]1[CH2:37][CH2:38][CH2:39][CH2:40][NH2:41].Cl>>[O:18]=[C:19]1[C:23]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)=[C:22]([C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=2)[C:21](=[O:36])[N:20]1[CH2:37][CH2:38][CH2:39][CH2:40][NH:41][C:9](=[O:11])[CH2:8][CH2:7][C:3]1[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 65578Oxalyl chlorideHCID 2596243-(Pyridin-3-yl)propanoic acidHCID 17921872HCID 17921872, compound

Product 1

HCID 17921856HCID 17921856, compound

Procedure

Batch size: 2.1 g (13.8 mmol) 3-(3-pyridyl)-propionic acid, 1.6 ml (47.4 mmol) oxalyl chloride, 3.8 ml (27.4 mmol) TEA and 4.0 g (12.5 mmol) 4-(2,5-dioxo-3,4-diphenyl-2,5-dihydropyrrol-1-yl)-butylamine•hydrochloride.

Sources & evidence

ORD record
ord-f8d5bab25d984996addd362cd3f95675
Source dataset
uspto-grants-2007_03
Patent number
US07192967B1

Reaction notes

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