HCID 18443689, compound → HCID 58822822, compound

Participants

Reaction Steps

This compound was prepared from (4-but-3-ynyloxy-phenyl)-phenylmethanone and (2S)-2-Methoxy-3-(4-trifluoromethane-sulfonyloxy-phenyl)-propionic acid ethyl ester (Example 1, Step A) following the procedure described in Example 38, Step C (66%). 1H-NMR (200.15 MHz, CDCl3): δ 37.85–7.73 (m, 4H), 7.57–7.43 (m; 3H), 7.34 (d, 2H, J=8.1), 7.16 (d, 2H, J=8.3), 7.00 (d, 2H, J=8.6), 4.25 (t, 2H, J=7.0), 4.18 (q, 2H, J=7.0), 3.92 (dd, 1H, J=7.3, 5.6), 3.34 (s, 3H), 3.01 (s, 1H), 2.98 (d, 1H, J=3.5), 2.93 (t, 2H, J=7.0), 1.23 (t, 3H, J=7.3).

Provenance & Evidence