HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[4-(4-oxo-2-phenyl-4H-chromen-6-yloxy)-but-1-ynyl]-phenyl}-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Hydroxyflavone | HCID 72279 | — |
| Edukt | Diisopropyl azodicarboxylate | HCID 5363146 | — |
| Edukt | Diethyl azodicarboxylate | HCID 5462977 | — |
| Edukt | 3-[4-(4-Hydroxy-but-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 69423017 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | (2S)-2-Methoxy-3-{4-[4-(4-oxo-2-phenyl-4H-chromen-6-yloxy)-but-1-ynyl]-phenyl}-propionic acid | HCID 58822632 | — |
Reaktionsschritte
The title compound was prepared from 3-[4-(4-Hydroxy-but-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 47, Step A and 6-hydroxyflavone following the standard coupling-hydrolysis procedure A using toluene as solvent and DIAD instead DEAD. MS(ES) for C29H24O6 [M+H]+: 469.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07192982B2 |
| Quelldatensatz | uspto-grants-2007_03 |
| ORD ID | ord-51a768f559a64c338bf48d6917780cfc |
| Quellennotiz | uspto-grants-2007_03 |