Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → (1r*,3s*)-3-(Biphenyl-4-yloxy)-cyclohexanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | (1R,3S)-(2S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 3-(biphenyl-4-yloxy)-1-cyclohexyl ester | HCID 58822646 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (1r*,3s*)-3-(Biphenyl-4-yloxy)-cyclohexanol | HCID 58822848 | — |
반응 단계
To a solution of compound from Step D in ethanol an excess of NaOH 1N was added and the mixture reaction was stirred at room temperature. The solution was concentrated in vacuo and diluted with brine. Extracted with ether and concentrated to yield the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07192982B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-fabca3168d024c9b968899996c0097b3 |
| 출처 메모 | uspto-grants-2007_03 |