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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459131Generated: October 29, 2026

p-(Trifluoromethoxy)phenol → HCID 58822828, compound

https://huagongshe.com/reaction/459131

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-(Trifluoromethoxy)phenolHCID 70015—
Reactant(2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acidHCID 69424952—
ProductHCID 58822828HCID 58822828—

Reaction Steps

The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 4-trifluoromethoxyphenol and cleavage from the resin (Standard Procedure G) gave an oily solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-3c734a45e19a47d39acc43cfe12b6f93
Source noteuspto-grants-2007_03