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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459181Generated: October 29, 2026

3-(4-Benzyloxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester → 3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester

https://huagongshe.com/reaction/459181

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Benzyloxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl esterHCID 69425304—
SolventEthyl AcetateHCID 8857—
Product3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58822833—

Reaction Steps

A solution of 3-(4-Benzyloxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester in ethyl acetate was treated with a catalytic amount of C—Pd (0.1 eq) and then H2 was bubbled through the mixture and stirred 2 hours. The mixture reaction was filtered through a pad of celite and concentrated in vacuo to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-2adc4350357a44c5a8aba22a3e04847d
Source noteuspto-grants-2007_03