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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459182Generated: October 29, 2026

1,1'-Biphenyl, 4-(3-bromopropoxy)- → (2S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-3-methyl-phenyl}-2-methoxy-propionic acid ethyl ester

https://huagongshe.com/reaction/459182

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-Biphenyl, 4-(3-bromopropoxy)-HCID 15233463—
Reactant3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58822833—
Product(2S)-3-{4-[3-(Biphenyl-4-yloxy)-propoxy]-3-methyl-phenyl}-2-methoxy-propionic acid ethyl esterHCID 58822867—

Reaction Steps

A mixture of 3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester and from Step E and 4-(3-bromopropoxy)biphenyl were treated under standard condition I to give the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-bcfc0f320a894d10a9b66717efd73f3a
Source noteuspto-grants-2007_03