Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459195Generated: October 30, 2026

Benzyl 4-hydroxyphenyl ketone → 2-Methoxy-3-{3-methoxy-4-[3-(4-phenylacetyl-phenoxy)-propoxy]-phenyl}-propionic acid

https://huagongshe.com/reaction/459195

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 4-hydroxyphenyl ketoneHCID 75607—
Reactant3-[4-(3-Bromo-propoxy)-3-methoxy-phenyl]-2-methoxy-propionic acidHCID 18443644—
Product2-Methoxy-3-{3-methoxy-4-[3-(4-phenylacetyl-phenoxy)-propoxy]-phenyl}-propionic acidHCID 69424874—

Reaction Steps

The title compound was prepared from 3-[4-(3-Bromo-propoxy)-3-methoxy-phenyl]-2-methoxy-propionic acid (Example 175, Step B) and 1-(4-Hydroxy-phenyl)-2-phenyl-ethanone following the Standard Procedure J. MS (ES) for C28H30O7 [M+H]+: 479.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-ec905759668a4276bc310d946b5a158a
Source noteuspto-grants-2007_03